Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 12/20 | 0.49 |
| ▸ | MMP1 | P03956 | 10/20 | 0.49 |
| ▸ | MMP13 | P45452 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759290 | 0.88 | ADAM17 (0.50) | ADAM17MMP1MMP13LMNATP53 | |
| SCHEMBL8433487 | 0.88 | MMP1 (0.43) | ADAM17MMP1MMP13 | |
| SCHEMBL8433497 | 0.88 | MMP1 (0.43) | ADAM17MMP1MMP13 | |
| SCHEMBL8436801 | 0.84 | NPC1 (0.43) | SMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL8570605 | 0.81 | ADAM17 (0.47) | ADAM17MMP1MMP13 | |
| SCHEMBL8570608 | 0.81 | ADAM17 (0.47) | ADAM17MMP1MMP13 | |
| SCHEMBL8432174 | 0.81 | MMP1 (0.61) | ADAM17MMP1MMP13 | |
| SCHEMBL8432172 | 0.81 | MMP1 (0.61) | ADAM17MMP1MMP13 | |
| SCHEMBL5760724 | 0.80 | MMP1 (0.71) | ADAM17MMP1 | |
| SCHEMBL7454737 | 0.80 | MMP1 (0.71) | ADAM17MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960098-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998034918-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-08-13 | — | — | WO | disclosed |