Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 13/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430992 | 0.89 | ABCB1 (0.62) | ABCB1HTR7 | |
| SCHEMBL8434186 | 0.88 | LMNA (0.75) | LMNAALDH1A1MAPTHTTTDP1 | |
| SCHEMBL8430999 | 0.88 | ABCB1 (0.61) | MAPTABCB1HTR7 | |
| Hydrochloric Acid SCHEMBL9005295 | 0.87 | LMNA (0.74) | LMNAALDH1A1MAPTHTTTDP1 | |
| SCHEMBL8433505 | 0.85 | POLB (0.63) | MAPTABCB1HTR7 | |
| SCHEMBL8432645 | 0.81 | MAPT (0.65) | LMNAALDH1A1MAPTABCB1 | |
| SCHEMBL8431138 | 0.78 | MAPT (0.69) | LMNAALDH1A1MAPTHTTTDP1 | |
| SCHEMBL8431150 | 0.77 | TP53 (0.63) | LMNAMAPTABCB1 | |
| SCHEMBL9866432 | 0.76 | TDP1 (0.70) | LMNAALDH1A1MAPTHTTTDP1 | |
| SCHEMBL9865013 | 0.76 | TDP1 (0.70) | LMNAALDH1A1MAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981530-A | FOR TREATMENT OF ALLERGIC DISEASES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |