Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13385838 | 0.81 | KIF11 (0.47) | KIF11CYP3A4TAAR1HSD17B10TDP1 | |
| SCHEMBL2849367 | 0.81 | ACHE (0.40) | KIF11HSD17B10GLAPOLBGAA | |
| SCHEMBL2871470 | 0.78 | KIF11 (0.49) | KIF11CYP3A4TAAR1HSD17B10TDP1 | |
| SCHEMBL29266608 | 0.78 | ACHE (0.40) | KIF11HSD17B10GLAPOLBGAA | |
| SCHEMBL25241147 | 0.77 | KIF11 (0.44) | KIF11CYP3A4TDP1GLAPOLB | |
| SCHEMBL30972576 | 0.77 | HSD17B10 (0.44) | KIF11CYP3A4TAAR1HSD17B10TDP1 | |
| SCHEMBL2202989 | 0.74 | ACHE (0.40) | KIF11HSD17B10GLAPOLBGAA | |
| SCHEMBL30972581 | 0.74 | HSD17B10 (0.44) | KIF11CYP3A4TAAR1HSD17B10TDP1 | |
| SCHEMBL20262955 | 0.73 | HSD17B10 (0.62) | CYP3A4TAAR1HSD17B10TDP1GLA | |
| SCHEMBL29720343 | 0.73 | ACHE (0.42) | KIF11HSD17B10POLBACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976710-A | HIGH DENSITY SEMICONDUCTORS; LOW THERMAL COEFFICIENT OF EXPANSION | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-11-02 | — | — | US | claimed |
| US-5115090-A | Polyamic acids and polyimides for multilayer elements, imsulators and passivation layers | INTERNATIONAL BUSINESS MACHINES CORPORATION | 1992-05-19 | — | — | US | claimed |
| US-5976710-A | HIGH DENSITY SEMICONDUCTORS; LOW THERMAL COEFFICIENT OF EXPANSION | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5310863-A | Polyimide materials with improved physico-chemical properties | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |