SCHEMBL2202989

SCHEMBL2202989

Nc1c(-c2ccccc2)cc(C(F)(F)F)c(C(F)(F)F)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.40
SMARCA2 P51531 1/20 0.38
SMARCA4 P51532 1/20 0.38
PBRM1 Q86U86 1/20 0.38
BACE1 P56817 2/20 0.38
HSD11B1 P28845 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
ADORA2A P29274 2/20 0.37
ADORA1 P30542 2/20 0.37
ADORA3 P0DMS8 1/20 0.37
HSD17B10 Q99714 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.36
MET P08581 1/20 0.36
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29266608 0.86 ACHE (0.40) ACHESMARCA2SMARCA4PBRM1BACE1
SCHEMBL2849367 0.86 ACHE (0.40) ACHEBACE1GLAPOLBGAA
SCHEMBL27920522 0.80 GLA (0.38) ACHEBACE1HSD11B1GLAPOLB
SCHEMBL6067691 0.79 KIF11 (0.39) ACHEBACE1HSD11B1GLAGAA
SCHEMBL28418773 0.79 SMARCA2 (0.36) ACHESMARCA2SMARCA4PBRM1BACE1
SCHEMBL29914846 0.76 KIF11 (0.45) ACHEBACE1HSD11B1KIF11S1PR1
SCHEMBL27974154 0.76 GLA (0.47) ACHEBACE1GLAPOLBGAA
SCHEMBL8917508 0.76 GLA (0.41) ACHEBACE1HSD11B1GLAPOLB
SCHEMBL28674664 0.75 KIF11 (0.46) ACHEBACE1GLAPOLBGAA
SCHEMBL8433508 0.74 KIF11 (0.41) ACHEBACE1GLAPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136750-A Diamino thioether compound and application thereof in self-repairing polyimide optical film 华中科技大学 2025-06-13 CN claimed
CN-120059250-A Method for regulating and controlling polyimide film high-temperature energy storage through regulating molecular structure 哈尔滨理工大学 2025-05-30 CN claimed
CN-119931050-A Polyimide emulsion sizing agent and preparation method thereof 中国航空制造技术研究院 2025-05-06 CN claimed
CN-119798106-A Diamine monomer, polyimide, preparation method and application thereof 中山大学 2025-04-11 CN claimed
CN-119636123-A Preparation method of polyimide resin composite material 中国航空制造技术研究院 2025-03-18 CN claimed
CN-119264868-A Polyimide mixed glue containing graphite and graphene and preparation process thereof 李恒飞 2025-01-07 CN claimed
CN-119192570-A Polyimide aerogel with radiation cooling characteristic and preparation method and application thereof 湘潭大学 2024-12-27 CN claimed
CN-118562127-B Preparation method of high Tg, low dielectric and intrinsic flame-retardant bio-based benzoxazine resin 中国科学技术大学 2024-10-11 CN claimed
CN-118698347-A High CO2/N2Selective hybridization carbon film and preparation method and application thereof 广东以色列理工学院 2024-09-27 CN claimed
CN-118290733-B Polyimide with high fluorine content, gas separation membrane, and preparation method and application thereof 大连理工大学 2024-08-30 CN claimed
CN-111205457-B Method for producing polyimide film 达迈科技股份有限公司 2022-09-23 CN claimed
CN-115055066-A Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2022-09-16 CN claimed
CN-114907565-A Fluorinated polyamide, preparation method thereof and polyamide film for flexible substrate 浙江中科玖源新材料有限公司 2022-08-16 CN claimed
CN-114488690-A Chemical amplification type negative polyimide photoresist and preparation method and application thereof 中国科学院化学研究所 2022-05-13 CN claimed
CN-111792646-B Polyimide modified nano silicon negative electrode material and preparation method and application thereof 苏州华赢新能源材料科技有限公司 2022-04-08 CN claimed
CN-109438704-B Polyimide film and preparation method thereof 无锡顺铉新材料有限公司 2022-04-01 CN claimed
CN-114196014-A Polyimide containing hexaazatriphenylene structure and preparation method thereof 大连理工大学 2022-03-18 CN claimed
CN-108658073-B Method for improving adsorption performance of activated carbon 深圳市环球绿地新材料有限公司 2020-11-03 CN claimed
CN-111792646-A Polyimide modified nano silicon negative electrode material and preparation method and application thereof 苏州华赢新能源材料科技有限公司 2020-10-20 CN claimed
US-20150030887-A1 MAGNETIC DEVICES WITH MOLECULAR OVERCOATS SEAGATE TECHNOLOGY LLC (US) 2015-01-29 US claimed