Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 3/20 | 0.45 |
| ▸ | KLK1 | P06870 | 2/20 | 0.45 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187679 | 0.83 | CSNK2A1 (0.67) | NPC1RAB9ATRPA1CSNK2A1MAPT | |
| SCHEMBL30578000 | 0.82 | NPC1 (0.56) | NPC1RAB9ATRPA1CSNK2A1IDO1 | |
| SCHEMBL1758035 | 0.82 | NPC1 (0.56) | NPC1RAB9ATRPA1CSNK2A1IDO1 | |
| SCHEMBL168869 | 0.80 | CSNK2A1 (0.69) | NPC1RAB9ATRPA1CSNK2A1MAPT | |
| SCHEMBL29495480 | 0.80 | ALDH1A1 (0.57) | NPC1RAB9ATRPA1CSNK2A1IDO1 | |
| SCHEMBL6856523 | 0.80 | NPC1 (0.55) | NPC1RAB9ATRPA1CSNK2A1IDO1 | |
| SCHEMBL11856735 | 0.80 | HSD11B1 (0.49) | NPC1RAB9ACSNK2A1TAS1R3TAS1R1 | |
| SCHEMBL760290 | 0.80 | ALDH1A1 (0.57) | NPC1RAB9ATRPA1CSNK2A1IDO1 | |
| Ammonia Solution, Strong SCHEMBL25336824 | 0.78 | CSNK2A1 (0.67) | NPC1RAB9ATRPA1CSNK2A1MAPT | |
| SCHEMBL14724818 | 0.78 | NPC1 (0.53) | NPC1RAB9ATRPA1CSNK2A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891995-A | Substituted benzhydrylamines as handles for solid phase peptide synthesis | AVENTIS PHARMACEUTICALS INC. | 1999-04-06 | — | — | US | disclosed |
| US-5684131-A | Substituted benzhydrylamines as handles for solid phase peptide synthesis | LEBL MICHAL (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0579785-B1 | SUBSTITUTED BENZHYDRYLAMINES AS HANDLES FOR SOLID PHASE PEPTIDE SYNTHESIS | LEBL MICHAL (US) | 1996-07-03 | — | — | EP | disclosed |