Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9005295 | 0.99 | LMNA (0.74) | LMNATDP1MAPTALDH1A1HTT | |
| SCHEMBL8434695 | 0.88 | L3MBTL1 (0.67) | HTTABCB1HTR7L3MBTL1 | |
| SCHEMBL8434205 | 0.88 | LMNA (0.69) | LMNATDP1MAPTALDH1A1HTT | |
| SCHEMBL8432590 | 0.86 | ABCB1 (0.61) | LMNAMAPTABCB1HTR7L3MBTL1 | |
| SCHEMBL8432330 | 0.85 | ABCB1 (0.60) | LMNAMAPTALDH1A1ABCB1HTR7 | |
| SCHEMBL7157651 | 0.81 | TDP1 (0.69) | LMNATDP1MAPTALDH1A1HTT | |
| SCHEMBL9866432 | 0.80 | TDP1 (0.70) | LMNATDP1MAPTALDH1A1HTT | |
| SCHEMBL9865921 | 0.80 | TDP1 (0.70) | LMNATDP1MAPTALDH1A1HTT | |
| SCHEMBL9865013 | 0.80 | TDP1 (0.70) | LMNATDP1MAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL9865660 | 0.79 | TDP1 (0.70) | LMNATDP1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981530-A | FOR TREATMENT OF ALLERGIC DISEASES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |