Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435195 | 0.85 | CTSB (0.42) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL7501514 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL8434256 | 0.65 | ALDH1A1 (0.44) | ALDH1A1HTTGAALMNASMN1; SMN2 | |
| SCHEMBL22807318 | 0.65 | HAO1 (0.49) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL24293770 | 0.62 | PTGIR (0.46) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1988387 | 0.62 | TAS1R3 (0.48) | ALDH1A1HTTSMN1; SMN2KDM4ETAS1R3 | |
| SCHEMBL7491139 | 0.61 | CTSB (0.44) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL6932815 | 0.61 | CA1 (0.77) | ALDH1A1LMNASMN1; SMN2KDM4EFFAR1 | |
| SCHEMBL7074737 | 0.61 | TAS1R3 (0.44) | ALDH1A1SMN1; SMN2TAS1R3TAS1R1MMP2 | |
| SCHEMBL10944697 | 0.60 | CA1 (0.44) | ALDH1A1HTTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932741-A | TREATING ILLNESSES RESULTING FROM ABNORMAL STIMULATION OF ENDOTHELIN RECEPTORS | HOECHST MARION ROUSSEL (FR) | 1999-08-03 | — | — | US | disclosed |