Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434256 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HTTGAAMAPTLMNA | |
| SCHEMBL6919672 | 0.87 | PARP1 (0.46) | ALDH1A1MEN1KMT2AGSK3BPARP1 | |
| SCHEMBL7491139 | 0.84 | CTSB (0.44) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8823589 | 0.77 | TUBB4A (0.50) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL8434259 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL3839556 | 0.76 | PARP1 (0.39) | ALDH1A1MAPTLMNAGSK3BPARP1 | |
| SCHEMBL6919860 | 0.74 | PARP1 (0.38) | ALDH1A1MAPTLMNAGSK3BPARP1 | |
| SCHEMBL8434261 | 0.73 | CNR2 (0.42) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL8435193 | 0.73 | SMN1; SMN2 (0.42) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL7489824 | 0.72 | THRB (0.40) | MEN1KMT2ALMNAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776325-B1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-11-20 | — | — | EP | disclosed |