Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501757 | 0.80 | EDNRA (0.55) | — | |
| SCHEMBL7501514 | 0.73 | ALDH1A1 (0.42) | CNR2ALDH1A1MEN1HTTKMT2A | |
| SCHEMBL7506638 | 0.69 | EDNRA (0.45) | ALDH1A1TLR7 | |
| SCHEMBL8434768 | 0.69 | EDNRA (0.52) | ALDH1A1 | |
| SCHEMBL7499877 | 0.67 | EDNRA (0.45) | ALDH1A1AGTR1AGTR2 | |
| SCHEMBL8434256 | 0.66 | ALDH1A1 (0.44) | ALDH1A1HTTGAA | |
| SCHEMBL29109902 | 0.66 | AGTR1 (0.48) | ALDH1A1MEN1KMT2ATLR7AGTR1 | |
| SCHEMBL8823608 | 0.65 | AGTR1 (0.59) | TLR7AGTR1AGTR2 | |
| SCHEMBL6422052 | 0.65 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL7706059 | 0.64 | AGTR1 (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932741-A | TREATING ILLNESSES RESULTING FROM ABNORMAL STIMULATION OF ENDOTHELIN RECEPTORS | HOECHST MARION ROUSSEL (FR) | 1999-08-03 | — | — | US | disclosed |