Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.58 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434242 | 0.87 | GID4 (0.60) | MAOBMAOASCN9A | |
| SCHEMBL8431818 | 0.87 | MAOB (0.72) | PARP10MAOBMAOASCN9A | |
| SCHEMBL8432752 | 0.80 | MAOB (0.56) | PARP10MAOBMAOASCN9AADAMTS4 | |
| SCHEMBL8433404 | 0.80 | NPC1 (0.64) | MAOBMAOA | |
| SCHEMBL8434262 | 0.78 | MAOB (0.58) | PARP15PARP10PARP14MAOBMAOA | |
| SCHEMBL5680071 | 0.78 | PARP15 (0.58) | PARP15PARP10PARP14MAOBMAOA | |
| SCHEMBL3967573 | 0.77 | PARP15 (0.60) | PARP15PARP10PARP14MAOBMAOA | |
| SCHEMBL8433725 | 0.76 | SCN9A (0.72) | PARP15PARP10PARP14MAOBMAOA | |
| SCHEMBL6029226 | 0.76 | FFAR1 (0.67) | PARP15PARP10PARP14MAOBMAOA | |
| SCHEMBL8434308 | 0.76 | MAOB (0.64) | PARP10MAOBMAOASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | claimed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |