Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910570 | 0.84 | PDK2 (0.38) | CRHR1CYP1A2CYP2A6TP53TDP1 | |
| SCHEMBL6562421 | 0.75 | CYP1A2 (0.59) | CYP1A2CYP2A6TP53TDP1ESR2 | |
| SCHEMBL20609436 | 0.74 | CYP2A6 (0.55) | CRHR1CYP1A2CYP2A6GAADHFR | |
| SCHEMBL1554672 | 0.74 | ALDH1A1 (0.48) | CYP1A2CYP2A6TP53TDP1ESR2 | |
| SCHEMBL29434190 | 0.74 | ALDH1A1 (0.48) | CYP1A2CYP2A6TP53TDP1ESR2 | |
| SCHEMBL23700154 | 0.72 | MYC (0.44) | CYP1A2TP53TDP1PDK2DRD2 | |
| SCHEMBL15673166 | 0.71 | PABPC1 (0.50) | CRHR1CYP1A2CYP2A6GAAPDK2 | |
| SCHEMBL2453274 | 0.71 | CYP1A2 (0.41) | CRHR1CYP1A2CYP2A6TDP1PDK2 | |
| SCHEMBL29444802 | 0.71 | CYP1A2 (0.41) | CRHR1CYP1A2CYP2A6TDP1PDK2 | |
| SCHEMBL29918191 | 0.70 | CYP1A2 (0.50) | CRHR1CYP1A2CYP2A6TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932649-A | ADDITION-CONDENSATION COPOLYMER | BRIDGESTONE CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0520279-B1 | Multilayer structures containing block copolymers of polysiloxanes and copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE CORP (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0832912-A2 | Block copolymers of polysiloxanes and copolymers of conjugated dienes and aromatic vinyl compounds, and multilayer structures containing same | Bridgestone Corporation (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5728782-A | IN THE PRESENCE OF ORGANOLITHIUM ANIONIC INITIATOR AND INERT PARTICLES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0476640-B1 | High performance tire treads and tires | BRIDGESTONE CORP (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0649861-B1 | 2,5-Substituted tetrahydrofurans as anionic initiator modifiers | BRIDGESTONE CORP (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5552483-A | Block copolymers of polysiloxanes and copolymers of conjugated dienes and aromatic vinyl compounds, and multilayer structures containing same | BRIDGESTONE CORPORATION (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0491199-B1 | Continuous process for preparing copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE CORP (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5489660-A | HIGH MOLECULAR WEIGHT ADDITION POLYMERS MADE BY USING TRI-METALLIZED 1-ALKYNES AS POLYMERIZATION CATALYSTS | BRIDGESTONE CORPORATION (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0476665-B1 | Oil extended ultra high molecular weight elastomers | BRIDGESTONE CORP (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0491229-A1 | Pneumatic tires for heavy-load vehicles | Bridgestone Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-5112929-A | Reaction of dienes to produce polymers with 1,2-microstructure | BRIDGESTONE CORPORATION (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0476640-A1 | High performance tire treads and tires | Bridgestone Corporation (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476665-A1 | Oil extended ultra high molecular weight elastomers | BRIDGESTONE CORPORATION (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476641-A1 | Ultra high molecular weight elastomer composition | BRIDGESTONE CORPORATION (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476662-A1 | Ultra high molecular weight copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0171497-B1 | CATALYST SYSTEM AND PROCESS FOR POLYMERIZING CONJUGATED DIENES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4591624-A | LITHIUM INITIATOR; CYCLIC ACETAL OF A GLYOXAL AND OPTIONALLY ORGANO MAGNESIUM OR ORGANOLALUMINUM COINITIATOR | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| EP-0171497-A1 | Catalyst system and process for polymerizing conjugated dienes | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| US-4520123-A | LITHIUM INITIATOR AND MODIFIER COMPRISING A CYCLIC ACETAL OF A GLYOXAL | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-05-28 | — | — | US | disclosed |