SCHEMBL2453274

SCHEMBL2453274

Cc1cc(C)c(-c2ccc3c4ccc(-c5c(C)cc(C)cc5C)c5cccc(c6cccc2c63)c54)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.41
CYP2A6 P11509 3/20 0.41
CRHR1 P34998 6/20 0.39
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.33
PABPC1 P11940 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDK2 Q15119 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
HPGD P15428 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ACHE P22303 1/20 0.32
CES2 O00748 1/20 0.32
KDM1A O60341 1/20 0.32
EED O75530 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444802 1.00 CYP1A2 (0.41) CYP1A2CYP2A6CRHR1MAPTKDM4E
SCHEMBL16801260 0.85 ADORA3 (0.36) CYP1A2CYP2A6CRHR1MAPTKDM4E
SCHEMBL2447864 0.85 CYP1A2 (0.46) CYP1A2CYP2A6MAPTKDM4EPABPC1
SCHEMBL29444830 0.85 CYP1A2 (0.46) CYP1A2CYP2A6MAPTKDM4EPABPC1
SCHEMBL15673166 0.85 PABPC1 (0.50) CYP1A2CYP2A6CRHR1MAPTKDM4E
SCHEMBL28073836 0.83 ALDH1A1 (0.55) CYP1A2CYP2A6CRHR1MAPTKDM4E
SCHEMBL21574544 0.79 CYP1A2 (0.56) CYP1A2CYP2A6CRHR1MAPTKDM4E
SCHEMBL12200467 0.79 CYP1A2 (0.39) CYP1A2CYP2A6CRHR1TDP1HPGD
SCHEMBL16800990 0.79 CYP1A2 (0.39) CYP1A2CYP2A6CRHR1MAPTKDM4E
SCHEMBL1557865 0.77 CYP1A2 (0.44) CYP1A2CYP2A6CRHR1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-11653565-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-05-16 US disclosed
US-11637250-B2 Polycyclic aromatic compound and light emitting layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-04-25 US disclosed
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-07 US disclosed
US-11539003-B2 Polycyclic aromatic amino compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-12-27 US disclosed
WO-2022185896-A1 POLYCYCLIC AROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 学校法人関西学院 2022-09-09 WO disclosed
EP-2669262-A1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC Corporation (JP) 2013-12-04 EP disclosed
US-20130292665-A1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC CORPORATION (JP) 2013-11-07 US disclosed
US-20130134405-A1 BENZOFLUORENE COMPOUND, EMISSION MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2013-05-30 US disclosed
EP-1640430-B1 Luminescent material and organic electroluminescent device using the same JNC CORP (JP) 2011-09-21 EP disclosed
EP-2177586-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2010-04-21 EP disclosed
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
US-20070212568-A1 Organic Electroluminescent Device CHISSO CORPORATION (JP) 2007-09-13 US disclosed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP disclosed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11539003-B2 Polycyclic aromatic amino compound BCAT2, BCAT1, SLC7A5 CYP1A2 3449/4885CYP2A6 3619/4885CRHR1 4180/4885
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC CYP1A2 3712/4885CYP2A6 4058/4885CRHR1 3967/4885
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device AOC2, TYR, BMI1 CYP1A2 1528/4885CYP2A6 2178/4885CRHR1 4802/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR CYP1A2 88/4885CYP2A6 303/4885CRHR1 244/4885
US-11653565-B2 Polycyclic aromatic compound ETV6, EBPL, EML4 CYP1A2 3552/4885CYP2A6 3847/4885CRHR1 4006/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 CYP1A2 393/4885CYP2A6 2384/4885CRHR1 4621/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 CYP1A2 1566/4885CYP2A6 2018/4885CRHR1 4570/4885
US-11637250-B2 Polycyclic aromatic compound and light emitting layer-forming composition C9, TYR, CCNA1 CYP1A2 48/4885CYP2A6 683/4885CRHR1 3269/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 CYP1A2 1566/4885CYP2A6 2018/4885CRHR1 4570/4885
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same C1S, EPB41, EPB41L2 CYP1A2 829/4885CYP2A6 1866/4885CRHR1 2435/4885
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 CYP1A2 1391/4885CYP2A6 2970/4885CRHR1 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.