Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895030 | 0.88 | EPHX1 (0.46) | CYP2C19POLBSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL15733043 | 0.85 | MAOB (0.54) | FFAR1PPARAPPARGLTA4HLMNA | |
| SCHEMBL8522004 | 0.78 | FFAR1 (0.51) | FFAR1GSK3BBACE1LTA4H | |
| SCHEMBL8522002 | 0.78 | CYP2C19 (0.43) | CYP2C19POLBSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL8435237 | 0.77 | CHRNB2 (0.43) | POLBSMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL8435236 | 0.76 | CYP2C19 (0.50) | CYP2C19ALDH1A1FFAR1PPARAPPARG | |
| SCHEMBL6388039 | 0.76 | APP (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9APTPN2 | |
| SCHEMBL13242652 | 0.76 | APP (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9APTPN2 | |
| SCHEMBL6525761 | 0.76 | NR4A2 (0.66) | POLBSMN1; SMN2ALDH1A1RXRARXRB | |
| SCHEMBL6743494 | 0.76 | RXRA (0.49) | CYP2C19SMN1; SMN2RXRARXRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |