Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522004 | 0.80 | FFAR1 (0.51) | GSK3BBACE1MMP12FFAR1FFAR4 | |
| SCHEMBL8435236 | 0.79 | CYP2C19 (0.50) | CYP2C19ALDH1A1GSK3BBACE1PPARG | |
| SCHEMBL8435239 | 0.78 | CYP2C19 (0.44) | CYP2C19ALDH1A1POLBCYP2C9SMN1; SMN2 | |
| SCHEMBL763259 | 0.74 | LMNA (0.60) | CYP2C19ALDH1A1SMN1; SMN2GSK3BBACE1 | |
| SCHEMBL8745182 | 0.72 | PPARA (0.41) | CYP2C19ALDH1A1PPARGPPARAFFAR1 | |
| SCHEMBL8522000 | 0.71 | PPARG (0.51) | ALDH1A1SMN1; SMN2GSK3BBACE1PPARG | |
| SCHEMBL2516876 | 0.71 | APP (0.58) | CYP2C19ALDH1A1SMN1; SMN2GSK3BBACE1 | |
| SCHEMBL15733043 | 0.71 | MAOB (0.54) | PPARGPPARAMAOBFFAR1FFAR4 | |
| SCHEMBL9331841 | 0.71 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2GSK3BBACE1PPARG | |
| SCHEMBL8435170 | 0.70 | ALDH1A1 (0.58) | CYP2C19ALDH1A1POLBCYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |