Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPOR | P19235 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522002 | 0.80 | CYP2C19 (0.43) | FFAR1FFAR4MMP12GSK3BBACE1 | |
| SCHEMBL8435236 | 0.79 | CYP2C19 (0.50) | FFAR1FFAR4GSK3BBACE1 | |
| SCHEMBL8435239 | 0.78 | CYP2C19 (0.44) | FFAR1LTA4HGSK3BBACE1 | |
| SCHEMBL763259 | 0.76 | LMNA (0.60) | GSK3BBACE1ALOX5 | |
| SCHEMBL8522000 | 0.73 | PPARG (0.51) | FFAR1FFAR4GSK3BBACE1ALOX5 | |
| SCHEMBL2516876 | 0.73 | APP (0.58) | FFAR1GSK3BBACE1 | |
| SCHEMBL9331841 | 0.73 | ALDH1A1 (0.68) | GSK3BBACE1 | |
| SCHEMBL1480744 | 0.72 | LMNA (0.55) | MMP12GSK3BBACE1 | |
| SCHEMBL8745182 | 0.72 | PPARA (0.41) | FFAR1FFAR4ALOX5 | |
| SCHEMBL6388039 | 0.71 | APP (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |