Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177824 | 1.00 | SLC6A3 (0.42) | SLC6A3SLC6A4SLC6A2OPRM1OPRL1 | |
| SCHEMBL8435345 | 0.86 | OPRM1 (0.41) | SLC6A3SLC6A4SLC6A2OPRM1OPRL1 | |
| SCHEMBL6524970 | 0.82 | SLC6A4 (0.51) | SLC6A3SLC6A4SLC6A2OPRM1OPRL1 | |
| SCHEMBL10612749 | 0.82 | OPRD1 (0.36) | CYP3A4 | |
| SCHEMBL11134373 | 0.82 | OPRM1 (0.32) | SLC6A3SLC6A4OPRM1OPRL1 | |
| SCHEMBL7734349 | 0.82 | SLC6A4 (0.43) | SLC6A3SLC6A4SLC6A2OPRM1OPRL1 | |
| SCHEMBL9775622 | 0.81 | FFAR1 (0.40) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9614557 | 0.80 | PARP15 (0.40) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9183435 | 0.80 | SLC6A4 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8822061 | 0.79 | KCNH2 (0.32) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454977-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-03 | — | — | US | disclosed |