SCHEMBL8435385

SCHEMBL8435385

CC(C)(C)c1ccc(Oc2ccc(C(=O)O)cc2)c(Oc2ccc(C(=O)O)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.53
RXRA P19793 5/20 0.52
RXRB P28702 4/20 0.52
NR4A2 P43354 1/20 0.52
RXRG P48443 2/20 0.52
TTR P02766 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
RARB P10826 1/20 0.49
RARG P13631 1/20 0.49
EPHX2 P34913 1/20 0.46
NR1H4 Q96RI1 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA9 Q16790 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
PARP15 Q460N3 1/20 0.45
PARP10 Q53GL7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8435173 0.98 SRD5A2 (0.51) SRD5A2RXRARXRBNR4A2RXRG
Hydrochloric Acid SCHEMBL8435178 0.98 SRD5A2 (0.51) SRD5A2RXRARXRBNR4A2RXRG
SCHEMBL19362944 0.83 SRD5A2 (0.69) SRD5A2RXRARXRBNR4A2RXRG
SCHEMBL8628820 0.82 TDP1 (0.49) TTRTDP1ALDH1A1HPGDPOLB
SCHEMBL19357374 0.81 RAB9A (0.56) SRD5A2RXRARXRBNR4A2TTR
SCHEMBL5581310 0.80 RXRA (0.55) SRD5A2RXRARXRBNR4A2TTR
SCHEMBL8435470 0.80 RXRA (0.48) SRD5A2RXRARXRBNR4A2RXRG
SCHEMBL8632254 0.79 TTR (0.55) SRD5A2RXRARXRBRXRGTTR
SCHEMBL9847750 0.79 ESRRA (0.53) SRD5A2RXRARXRBNR4A2RXRG
Hydrochloric Acid SCHEMBL8432428 0.79 RXRA (0.47) SRD5A2RXRARXRBNR4A2RXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5965690-A A POLYESTER, A FUSIBLE POLYAMIDE OR A POLYAMIDEESTER USEFUL FOR MOLDING RESINS AND COATINGS UNIVERSITY OF LIVERPOOL (GB) 1999-10-12 US disclosed
US-5834620-A MONOMERS FOR MOLDING MATERIALS, COATINGS UNIVERSITY OF LIVERPOOL (GB) 1998-11-10 US disclosed
EP-0757702-B1 POLY (IMIDE-ETHERS) DU PONT (US) 1998-07-01 EP disclosed
EP-0833856-A1 AROMATIC POLYAMIDES AND POLYESTERS CONTAINING ORTHO-ETHER GROUPS THE UNIVERSITY OF LIVERPOOL (GB) 1998-04-08 EP disclosed
US-5675020-A CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES THE UNIVERSITY OF LIVERPOOL (GB) 1997-10-07 US disclosed
WO-1997000903-A1 AROMATIC POLYAMIDES AND POLYESTERS CONTAINING ORTHO-ETHER GROUPS THE UNIVERSITY OF LIVERPOOL (GB) 1997-01-09 WO disclosed
US-5434240-A Films. fibers, encapsulation, thermoplastics THE UNIVERSITY OF LIVERPOOL (GB) 1995-07-18 US disclosed