SCHEMBL8632254

SCHEMBL8632254

Cc1ccc(Oc2ccc(C(=O)O)cc2)c(Oc2ccc(C(=O)O)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.55
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
RXRA P19793 3/20 0.52
GFER P55789 1/20 0.51
PARP15 Q460N3 1/20 0.49
PARP10 Q53GL7 1/20 0.49
SRD5A2 P31213 3/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
RXRB P28702 2/20 0.45
RXRG P48443 1/20 0.45
MMP13 P45452 1/20 0.45
CA12 O43570 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA7 P43166 1/20 0.44
TPMT P51580 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15010714 0.92 TTR (0.59) TTRALDH1A1SMN1; SMN2RXRAGFER
SCHEMBL11602800 0.88 RXRA (0.58) TTRALDH1A1SMN1; SMN2RXRAGFER
SCHEMBL15011327 0.87 HTT (0.51) TTRALDH1A1SMN1; SMN2RXRAGFER
SCHEMBL27373055 0.82 MRGPRX4 (0.55) TTRALDH1A1SMN1; SMN2RXRAMMP13
SCHEMBL26563282 0.81 RXRA (0.55) TTRALDH1A1SMN1; SMN2RXRAGFER
SCHEMBL6034956 0.81 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2RXRAGFERPARP15
SCHEMBL8628744 0.80 ALDH1A1 (0.51) ALDH1A1GFER
SCHEMBL21628442 0.79 MAPK1 (0.61) TTRALDH1A1SMN1; SMN2RXRAGFER
SCHEMBL8435385 0.79 SRD5A2 (0.53) TTRALDH1A1RXRAPARP15PARP10
Hydrochloric Acid SCHEMBL8435173 0.78 SRD5A2 (0.51) TTRALDH1A1RXRASRD5A2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757702-B1 POLY (IMIDE-ETHERS) DU PONT (US) 1998-07-01 EP disclosed
US-5675020-A CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES THE UNIVERSITY OF LIVERPOOL (GB) 1997-10-07 US disclosed
US-5434240-A Films. fibers, encapsulation, thermoplastics THE UNIVERSITY OF LIVERPOOL (GB) 1995-07-18 US disclosed