Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.48 |
| ▸ | RXRB | P28702 | 4/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8432435 | 0.99 | RXRA (0.47) | RXRARXRBRXRGNR4A2SRD5A2 | |
| Hydrochloric Acid SCHEMBL8432428 | 0.99 | RXRA (0.47) | RXRARXRBRXRGNR4A2SRD5A2 | |
| SCHEMBL8630248 | 0.84 | ALDH1A1 (0.43) | RXRBTDP1ALDH1A1 | |
| SCHEMBL9847750 | 0.81 | ESRRA (0.53) | RXRARXRBRXRGNR4A2SRD5A2 | |
| SCHEMBL8435385 | 0.80 | SRD5A2 (0.53) | RXRARXRBRXRGNR4A2SRD5A2 | |
| Hydrochloric Acid SCHEMBL8435178 | 0.78 | SRD5A2 (0.51) | RXRARXRBRXRGNR4A2SRD5A2 | |
| Hydrochloric Acid SCHEMBL8435173 | 0.78 | SRD5A2 (0.51) | RXRARXRBRXRGNR4A2SRD5A2 | |
| SCHEMBL8433560 | 0.76 | KIF11 (0.42) | MAPTMAPK1SMN1; SMN2PARP15PARP10 | |
| SCHEMBL9847810 | 0.75 | RARG (0.64) | RXRARXRBRXRGESRRARARB | |
| SCHEMBL19362944 | 0.75 | SRD5A2 (0.69) | RXRARXRBRXRGNR4A2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965690-A | A POLYESTER, A FUSIBLE POLYAMIDE OR A POLYAMIDEESTER USEFUL FOR MOLDING RESINS AND COATINGS | UNIVERSITY OF LIVERPOOL (GB) | 1999-10-12 | — | — | US | disclosed |
| US-5834620-A | MONOMERS FOR MOLDING MATERIALS, COATINGS | UNIVERSITY OF LIVERPOOL (GB) | 1998-11-10 | — | — | US | disclosed |
| EP-0757702-B1 | POLY (IMIDE-ETHERS) | DU PONT (US) | 1998-07-01 | — | — | EP | disclosed |
| EP-0833856-A1 | AROMATIC POLYAMIDES AND POLYESTERS CONTAINING ORTHO-ETHER GROUPS | THE UNIVERSITY OF LIVERPOOL (GB) | 1998-04-08 | — | — | EP | disclosed |
| US-5675020-A | CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES | THE UNIVERSITY OF LIVERPOOL (GB) | 1997-10-07 | — | — | US | disclosed |
| WO-1997000903-A1 | AROMATIC POLYAMIDES AND POLYESTERS CONTAINING ORTHO-ETHER GROUPS | THE UNIVERSITY OF LIVERPOOL (GB) | 1997-01-09 | — | — | WO | disclosed |
| US-5434240-A | Films. fibers, encapsulation, thermoplastics | THE UNIVERSITY OF LIVERPOOL (GB) | 1995-07-18 | — | — | US | disclosed |