SCHEMBL8438006

SCHEMBL8438006

CCCCOC(C)N(CC)c1cccc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.39
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 2/20 0.39
GPX4 P36969 1/20 0.39
PAX8 Q06710 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.35
HSD17B1 P14061 2/20 0.35
HSD17B2 P37059 2/20 0.35
POLQ O75417 2/20 0.34
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
TSHR P16473 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX5 P09917 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17101219 0.86 MAPT (0.39) TP53MAPTNPC1RAB9AALDH1A1
SCHEMBL8435490 0.85 MAPT (0.42) TP53MAPTNPC1RAB9AALDH1A1
SCHEMBL28648836 0.82 TP53 (0.40) TP53MAPTALDH1A1POLQHTT
SCHEMBL11321042 0.80 MAPT (0.43) TP53MAPTALDH1A1POLQHTT
SCHEMBL8435801 0.80 ALDH1A1 (0.44) TP53MAPTNPC1RAB9AALDH1A1
SCHEMBL11676404 0.79 HSD17B1 (0.42) TP53MAPTNPC1RAB9AALDH1A1
SCHEMBL11679587 0.79 TP53 (0.44) TP53MAPTNPC1RAB9AALDH1A1
SCHEMBL6296733 0.78 S100B (0.49) ALDH1A1TSHR
SCHEMBL11674444 0.78 HSD17B1 (0.42) TP53MAPTHSD17B1HSD17B2POLQ
SCHEMBL11674832 0.77 NPC1 (0.43) TP53MAPTNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883232-A DIAZAHEMICYANINE, TRIAZOLE, AZO AND HYDROPHOBIC DYES; COLORFASTNESS, COLOR REPRODUCIBILITY SONY CORPORATION (JP) 1999-03-16 US disclosed
US-5834600-A DIAZAHEMICYANINE DYES, MAGENTA, IMPROVED PHOTOSTABILITY AND REPRODUCIBILITY SONY CORPORATION (JP) 1998-11-10 US disclosed
EP-0751188-B1 Hydrophobic cationic dyes and thermal transfer ink ribbons using the same SONY CORP (JP) 1998-08-26 EP disclosed
EP-0751188-A1 Hydrophobic cationic dyes and thermal transfer ink ribbons using the same SONY CORPORATION (JP) 1997-01-02 EP disclosed