SCHEMBL8435809

SCHEMBL8435809

COc1ccc(C(OC(c2ccc(OC)cc2)c2ccc(Cl)c(C)c2)c2ccc(Cl)c(C)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 2/20 0.39
NPY1R P25929 1/20 0.39
NPY2R P49146 1/20 0.39
MCHR1 Q99705 1/20 0.39
KMT2A Q03164 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MCL1 Q07820 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
ACHE P22303 1/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8439067 0.85 ALDH1A1 (0.42) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL9771568 0.84 L3MBTL1 (0.42) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL9771543 0.83 KMT2A (0.43) TSHRALDH1A1TDP1L3MBTL1MAPT
SCHEMBL3389444 0.80 CA1 (0.58) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL8440000 0.78 HPGD (0.50) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL9771561 0.78 ACHE (0.42) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL9765970 0.76 ACHE (0.65) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL130126 0.76 MCL1 (0.52) TSHRALDH1A1L3MBTL1MAPTNPY1R
SCHEMBL9771632 0.75 TDP1 (0.43) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL8435813 0.73 MAPT (0.44) TSHRALDH1A1L3MBTL1MAPTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4981835-A BENZYL ETHER DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US claimed
JP-3218888-A None JP disclosed
EP-0963858-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1999-12-15 EP disclosed
EP-0844099-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-05-27 EP disclosed
US-5661101-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1997-08-26 US disclosed
JP-H03218888-A THERMAL RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1991-09-26 JP disclosed
EP-0408339-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-16 EP disclosed
US-4981835-A BENZYL ETHER DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed