Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | GLA | P06280 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400876 | 0.86 | MAPK1 (0.58) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL30570855 | 0.84 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8142110 | 0.84 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31015931 | 0.84 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2955131 | 0.84 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL4656286 | 0.83 | CES2 (0.61) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL3494392 | 0.83 | MAPK1 (0.65) | KDM4EALDH1A1MAPTGAAATM | |
| SCHEMBL8412494 | 0.82 | NPSR1 (0.74) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL8139074 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2961556 | 0.80 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969146-A | MONOAMINE OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-10-19 | — | — | US | disclosed |