Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852632 | 0.79 | MEN1 (0.37) | — | |
| SCHEMBL28305379 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL3178600 | 0.69 | ALDH1A1 (0.36) | L3MBTL1 | |
| SCHEMBL2489254 | 0.66 | FDPS (0.35) | L3MBTL1 | |
| SCHEMBL4087218 | 0.66 | ALDH1A1 (0.33) | L3MBTL1 | |
| SCHEMBL5665801 | 0.64 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL15647631 | 0.64 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL7670377 | 0.64 | MAPT (0.42) | MAPTL3MBTL1HTT | |
| SCHEMBL7216621 | 0.63 | — | — | |
| SCHEMBL6471708 | 0.63 | KDM4C (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-B1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN CO LLC (US) | 2012-03-28 | — | — | EP | disclosed |