Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 6/20 | 0.52 |
| ▸ | CES1 | P23141 | 6/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL625507 | 0.92 | TSHR (0.61) | NAPRTDAOTSHRCES2CES1 | |
| Benzoic Acid SCHEMBL6130390 | 0.92 | TSHR (0.61) | NAPRTDAOTSHRCES2CES1 | |
| Benzoic Acid SCHEMBL28364663 | 0.90 | TSHR (0.58) | NAPRTDAOTSHRCES2CES1 | |
| Catechol SCHEMBL28191561 | 0.90 | HDAC3 (0.59) | CES2CES1HDAC3HDAC1HDAC2 | |
| Benzoic Acid SCHEMBL20985706 | 0.89 | DAO (0.56) | NAPRTDAOTSHRCES2CES1 | |
| Terephthalic Acid SCHEMBL9943962 | 0.84 | FFAR3 (0.62) | TSHRHDAC3HDAC1HDAC2HDAC8 | |
| Benzoic Acid SCHEMBL7669891 | 0.82 | TSHR (0.78) | NAPRTDAOTSHRCES2CES1 | |
| Benzoic Acid SCHEMBL2019528 | 0.82 | TSHR (0.78) | NAPRTDAOTSHRCES2CES1 | |
| Salicylic Acid SCHEMBL28044508 | 0.81 | ALDH1A1 (0.67) | NAPRTTSHRCES2CES1HDAC3 | |
| Benzoic Acid SCHEMBL5787758 | 0.81 | CES2 (0.61) | NAPRTDAOTSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699543-B1 | Printing paper | SONY CORP (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5635441-A | SHEET SUBSTRATE HAVING DYE RECEIVING LAYER OF CROSSLINKED COATING OBTAINED BY CURING MIXTURE OF BUTYRAL RESIN, VINYLPHENOLIC RESIN, POLYISOCYANATE; STORAGE STABLE IMAGES | SONY CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0699543-A1 | Printing paper | SONY CORPORATION (JP) | 1996-03-06 | — | — | EP | disclosed |