Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432493 | 0.71 | POLB (0.35) | POLB | |
| SCHEMBL19650029 | 0.70 | PKM (0.50) | ALDH1A1MAPTMAPK1HTTCYP1A2 | |
| SCHEMBL8436837 | 0.66 | MEN1 (0.32) | ALDH1A1MAPTLMNA | |
| SCHEMBL19650567 | 0.64 | PKM (0.37) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL8432458 | 0.63 | MAPK1 (0.34) | ALDH1A1MAPTMAPK1HTTLMNA | |
| SCHEMBL6979768 | 0.62 | ALDH1A1 (0.44) | ALDH1A1MAPTHTT | |
| SCHEMBL9357054 | 0.61 | PTGS1 (0.55) | ALDH1A1MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL9587667 | 0.61 | ALDH1A1 (0.41) | ALDH1A1MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL10686367 | 0.61 | PKM (0.44) | ALDH1A1MAPTMAPK1HTTLMNA | |
| SCHEMBL9080078 | 0.61 | ALDH1A1 (0.31) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869686-A | Substituted pyrazole derivatives, processes for their preparation and their use as herbicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| US-5756424-A | POTENTIATION | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5580986-A | HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-03 | — | — | US | disclosed |