Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436203 | 0.89 | SPR (0.40) | MAPK1PTGS2KMT2ASMN1; SMN2SPR | |
| SCHEMBL8436843 | 0.88 | MKNK1 (0.36) | MAPK1KMT2ASMN1; SMN2SPRNPC1 | |
| SCHEMBL8434097 | 0.85 | TSHR (0.41) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8436775 | 0.79 | PTPN1 (0.37) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27364168 | 0.78 | ACHE (0.31) | — | |
| SCHEMBL8921979 | 0.77 | TSHR (0.53) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27291964 | 0.76 | — | — | |
| SCHEMBL8432677 | 0.76 | KMT2A (0.32) | KMT2A | |
| SCHEMBL27417001 | 0.70 | NPC1 (0.30) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9213542 | 0.69 | PTGS2 (0.32) | MAPK1PTGS2KMT2ASPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869686-A | Substituted pyrazole derivatives, processes for their preparation and their use as herbicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0663913-B1 | NEW SUBSTITUTED PYRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-07-29 | — | — | EP | disclosed |
| US-5756424-A | POTENTIATION | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| CN-1161965-A | Substituted pyrazole derivatives | SCHERING AG (DE) | 1997-10-15 | — | — | CN | disclosed |
| US-5580986-A | HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-03 | — | — | US | disclosed |
| CN-1087342-A | Novel substituted pyrazole derivatives, process for their preparation and their use as herbicides | SCHERING AG (DE) | 1994-06-01 | — | — | CN | disclosed |