Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440239 | 0.89 | CYP2D6 (0.43) | HTTCYP2D6CYP1A2LTA4HCYP2C9 | |
| SCHEMBL8437407 | 0.83 | MEN1 (0.39) | CYP1A2KDM4EKCNH2KMT2AMAPT | |
| Diethylamine SCHEMBL8437515 | 0.82 | MEN1 (0.40) | CYP1A2KDM4EKMT2AMAPTCHRNA7 | |
| SCHEMBL8818120 | 0.79 | CHEK1 (0.45) | HTTCYP2D6CYP1A2LTA4HCYP2C9 | |
| SCHEMBL8441865 | 0.79 | MEN1 (0.40) | KDM4EKCNH2KMT2AMAPTNPSR1 | |
| SCHEMBL8441206 | 0.75 | MEN1 (0.54) | HTTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8441127 | 0.72 | MEN1 (0.41) | KDM4EKMT2AMAPTCHRNA7NPSR1 | |
| Diethylamine SCHEMBL8818126 | 0.71 | CHEK1 (0.42) | HTTCYP1A2KDM4EKCNH2MCHR1 | |
| SCHEMBL8441513 | 0.70 | MAOB (0.43) | CYP1A2LTA4HCYP2C19KDM4EKMT2A | |
| SCHEMBL8816075 | 0.68 | CHEK1 (0.46) | HTTKDM4EMAPTNPSR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955472-A | INHIBITION OF AMYLOID AGGREGATION IN ANIMALS AND PREVENTION OF ALZHEIMER'S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-09-21 | — | — | US | claimed |