Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438657 | 0.97 | RECQL (0.39) | RECQLDPP8DPP9MCHR1TDP1 | |
| SCHEMBL8434836 | 0.93 | KMT2A (0.39) | DPP8DPP9MCHR1TDP1NPBWR1 | |
| SCHEMBL8440372 | 0.91 | RECQL (0.37) | RECQLDPP8DPP9MCHR1TDP1 | |
| SCHEMBL8440852 | 0.91 | RECQL (0.37) | RECQLDPP8DPP9MCHR1TDP1 | |
| SCHEMBL8576679 | 0.88 | CCR5 (0.37) | TDP1CCR5 | |
| SCHEMBL8438542 | 0.87 | ALDH1A1 (0.36) | RECQLDPP8DPP9MCHR1TDP1 | |
| SCHEMBL8441151 | 0.87 | MCHR1 (0.35) | RECQLDPP8DPP9MCHR1TDP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8576424 | 0.85 | DPP8 (0.35) | RECQLDPP8DPP9MCHR1TDP1 | |
| SCHEMBL8440273 | 0.84 | RECQL (0.36) | RECQLMCHR1TDP1NPBWR1CCR5 | |
| Trifluoromethanesulfonic Acid SCHEMBL8436309 | 0.84 | KMT2A (0.36) | DPP8DPP9MCHR1TDP1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |