Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434836 | 0.90 | KMT2A (0.39) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL8438656 | 0.89 | CCR5 (0.35) | KMT2ADPP8DPP9MCHR1TDP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8576424 | 0.87 | DPP8 (0.35) | DPP8DPP9NPBWR1MCHR1TDP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8541838 | 0.86 | PDK1 (0.35) | KMT2AALDH1A1LMNAMAPTDPP8 | |
| SCHEMBL8438657 | 0.86 | RECQL (0.39) | KMT2AALDH1A1MAPTDPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL8440244 | 0.85 | CCR5 (0.34) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL8439500 | 0.85 | ALDH1A1 (0.40) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL8438004 | 0.84 | RECQL (0.38) | DPP8DPP9NPBWR1MCHR1TDP1 | |
| SCHEMBL8438542 | 0.83 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTDPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL8436590 | 0.83 | SMN1; SMN2 (0.39) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |