Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441151 | 0.98 | MCHR1 (0.35) | RECQLTDP1ALDH1A1MAPTTP53 | |
| SCHEMBL8437058 | 0.91 | NPBWR1 (0.38) | TDP1ALDH1A1MAPTTP53MCHR1 | |
| SCHEMBL8434757 | 0.89 | ALDH1A1 (0.41) | TDP1ALDH1A1MAPTTP53MCHR1 | |
| SCHEMBL8440852 | 0.89 | RECQL (0.37) | RECQLTDP1MCHR1NPBWR1KMT2A | |
| SCHEMBL8440008 | 0.88 | ALDH1A1 (0.37) | TDP1ALDH1A1MAPTTP53MCHR1 | |
| SCHEMBL8438542 | 0.87 | ALDH1A1 (0.36) | RECQLTDP1ALDH1A1MAPTTP53 | |
| SCHEMBL8439607 | 0.87 | SMN1; SMN2 (0.39) | ALDH1A1MAPTMCHR1NPBWR1KMT2A | |
| SCHEMBL8438657 | 0.87 | RECQL (0.39) | RECQLTDP1ALDH1A1MAPTMCHR1 | |
| SCHEMBL8440372 | 0.85 | RECQL (0.37) | RECQLTDP1ALDH1A1MAPTMCHR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438656 | 0.84 | CCR5 (0.35) | RECQLTDP1MCHR1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |