SCHEMBL95222

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8438009	0.87	NPC1 (0.45)	SIGMAR1NPC1JAK2RAB9APAX8
	SCHEMBL94752	0.83	TAAR1 (0.44)	SIGMAR1TAAR1ALDH1A1DRD1
	SCHEMBL27329621	0.82	ADRA2C (0.37)	SIGMAR1TAAR1
	SCHEMBL25684761	0.79	TAAR1 (0.39)	SIGMAR1TAAR1ALDH1A1GLATSHR
	SCHEMBL94876	0.79	TSHR (0.38)	SIGMAR1TAAR1ALDH1A1GLATSHR
	SCHEMBL3956329	0.79	TAAR1 (0.39)	SIGMAR1TAAR1ALDH1A1GLATSHR
	SCHEMBL17045962	0.78	TAAR1 (0.38)	SIGMAR1TAAR1ALDH1A1GLATSHR
	SCHEMBL1812827	0.75	ESRRG (0.34)	NPC1JAK2RAB9APAX8KCNH2
	SCHEMBL8436030	0.75	NPC1 (0.44)	SIGMAR1NPC1JAK2RAB9APAX8
	SCHEMBL2545305	0.75	TSHR (0.41)	SIGMAR1TAAR1ALDH1A1GLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.