Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.72 |
| ▸ | MITF | O75030 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438572 | 0.80 | ATM (0.47) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL6140211 | 0.79 | LMNA (0.67) | ALDH1A1HTTKMT2ATDP1MAPT | |
| SCHEMBL11853098 | 0.75 | ALDH1A1 (0.62) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL2869405 | 0.75 | HTR6 (0.61) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL28157462 | 0.74 | NR4A1 (0.61) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL230930 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL29612638 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL600333 | 0.72 | APEX1 (0.51) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL30768131 | 0.72 | APEX1 (0.51) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL11541896 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HSP90AA1ATMNPSR1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602228-A | Nickel phosphate catalysts | MAXDEM INCORPORATED (US) | 1997-02-11 | — | — | US | claimed |
| WO-1996039455-A1 | NICKEL PHOSPHITE CATALYSTS | MAXDEM INCORPORATED (US) | 1996-12-12 | — | — | WO | claimed |
| US-5858907-A | Nickel phosphite catalysts | MAXDEM, INCORPORATED (US) | 1999-01-12 | — | — | US | disclosed |
| US-5602228-A | Nickel phosphate catalysts | MAXDEM INCORPORATED (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996039455-A1 | NICKEL PHOSPHITE CATALYSTS | MAXDEM INCORPORATED (US) | 1996-12-12 | — | — | WO | disclosed |