Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8576424 | 0.98 | DPP8 (0.35) | CCR5RECQLTDP1DPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL8440244 | 0.91 | CCR5 (0.34) | CCR5RECQLATM | |
| SCHEMBL8440852 | 0.91 | RECQL (0.37) | RECQLTDP1DPP8DPP9KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL8541838 | 0.90 | PDK1 (0.35) | CCR5RECQLDPP8DPP9PDK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8539389 | 0.90 | PDK1 (0.36) | CCR5TDP1PDK1PDK2PDK3 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438307 | 0.90 | PDK1 (0.36) | CCR5TDP1PDK1PDK2PDK3 | |
| Trifluoromethanesulfonic Acid SCHEMBL8436309 | 0.89 | KMT2A (0.36) | TDP1DPP8DPP9KMT2AMCHR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8435836 | 0.88 | CCR5 (0.36) | CCR5DPP8DPP9PDK1PDK2 | |
| Trifluoromethanesulfonic Acid SCHEMBL9125753 | 0.87 | CCR5 (0.39) | CCR5DPP8DPP9PDK1PDK2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8537325 | 0.87 | CCR5 (0.37) | CCR5DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |