Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8434762 | 0.98 | CCR5 (0.35) | CCR5ALDH1A1NPBWR1MCHR1DPP8 | |
| SCHEMBL8440008 | 0.93 | ALDH1A1 (0.37) | CCR5ALDH1A1NPBWR1MCHR1MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL8438684 | 0.92 | PDK1 (0.39) | CCR5ALDH1A1DPP8DPP9PDK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL9125753 | 0.89 | CCR5 (0.39) | CCR5ALDH1A1NPBWR1MCHR1DPP8 | |
| SCHEMBL8437058 | 0.88 | NPBWR1 (0.38) | ALDH1A1NPBWR1MCHR1DPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438656 | 0.88 | CCR5 (0.35) | CCR5MCHR1DPP8DPP9PDK1 | |
| SCHEMBL8434757 | 0.86 | ALDH1A1 (0.41) | ALDH1A1NPBWR1MCHR1DPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL9127836 | 0.86 | CCR5 (0.37) | CCR5NPBWR1MCHR1DPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL8576424 | 0.86 | DPP8 (0.35) | CCR5NPBWR1MCHR1DPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438327 | 0.85 | CCR5 (0.36) | CCR5DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |