Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574384 | 0.94 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL9574276 | 0.94 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL8435826 | 0.93 | EPHX2 (0.38) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL9574308 | 0.91 | ATM (0.38) | DPP8DPP9ALDH1A1MAPTATM | |
| SCHEMBL9574341 | 0.89 | DPP8 (0.35) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL9574214 | 0.89 | DPP8 (0.35) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL8439220 | 0.87 | DPP8 (0.43) | DPP8DPP9ALDH1A1MAPTATM | |
| SCHEMBL9578034 | 0.85 | ALDH1A1 (0.37) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL8540849 | 0.84 | EPHX2 (0.36) | DPP8DPP9ALDH1A1MAPTATM | |
| SCHEMBL9574265 | 0.84 | DPP8 (0.40) | DPP8DPP9ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |