Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574276 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNAEPHX2DPP8DPP9 | |
| SCHEMBL8435826 | 0.96 | EPHX2 (0.38) | ALDH1A1LMNAEPHX2DPP8DPP9 | |
| SCHEMBL8439013 | 0.94 | DPP8 (0.36) | ALDH1A1LMNADPP8DPP9ATM | |
| SCHEMBL8540849 | 0.91 | EPHX2 (0.36) | ALDH1A1EPHX2DPP8DPP9SIGMAR1 | |
| SCHEMBL9574306 | 0.90 | ALDH1A1 (0.36) | ALDH1A1LMNAEPHX2DPP8DPP9 | |
| SCHEMBL8102813 | 0.89 | SIGMAR1 (0.33) | ALDH1A1LMNAEPHX2DPP8DPP9 | |
| SCHEMBL8435987 | 0.88 | HSD11B1 (0.44) | ALDH1A1EPHX2DPP8DPP9SIGMAR1 | |
| SCHEMBL8435984 | 0.88 | HSD11B1 (0.44) | ALDH1A1EPHX2DPP8DPP9SIGMAR1 | |
| SCHEMBL8439767 | 0.87 | EPHX2 (0.39) | ALDH1A1EPHX2DPP8DPP9SIGMAR1 | |
| SCHEMBL8542381 | 0.86 | SIGMAR1 (0.35) | ALDH1A1LMNAEPHX2DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |