Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540849 | 0.93 | EPHX2 (0.36) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL8439767 | 0.93 | EPHX2 (0.39) | ATMMMP2ANPEPALDH1A1EPHX1 | |
| SCHEMBL8439013 | 0.91 | DPP8 (0.36) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL8580350 | 0.90 | MMP2 (0.36) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL8439220 | 0.87 | DPP8 (0.43) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL9578034 | 0.86 | ALDH1A1 (0.37) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL9574384 | 0.84 | ALDH1A1 (0.36) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL9574276 | 0.84 | ALDH1A1 (0.36) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL8540640 | 0.84 | EPHX2 (0.35) | ATMMMP2ANPEPALDH1A1MAPT | |
| SCHEMBL8542239 | 0.84 | EPHX2 (0.35) | ATMMMP2ANPEPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |