SCHEMBL8439475

SCHEMBL8439475

O=C(O)CSc1c(F)cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1F

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 3/20 0.59
TBXAS1 P24557 3/20 0.53
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PRMT1 Q99873 2/20 0.49
AKR1C3 P42330 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438979 0.91 TAAR1 (0.58) TBXA2RTBXAS1MEN1KMT2A
SCHEMBL8442601 0.89 TAAR1 (0.52) TBXA2RTBXAS1MEN1KMT2APRMT1
SCHEMBL8438739 0.88 ALDH1A1 (0.56) TBXAS1MEN1KMT2AAKR1C3
SCHEMBL8437940 0.88 TBXAS1 (0.50) TBXA2RTBXAS1MEN1KMT2A
SCHEMBL8438622 0.88 TBXA2R (0.59) TBXA2RTBXAS1MEN1KMT2APRMT1
SCHEMBL8441016 0.85 ALDH1A1 (0.59) MEN1KMT2AAKR1C3
SCHEMBL8441089 0.85 CA1 (0.53) TBXA2RTBXAS1MEN1KMT2A
SCHEMBL9510805 0.81 TBXA2R (0.60) TBXA2RTBXAS1
SCHEMBL9754213 0.81 TBXA2R (0.69) TBXA2RTBXAS1PRMT1AKR1C3
SCHEMBL8441823 0.79 MCL1 (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5955505-A TREATING NERVE DEGENERATIVE DISORDERS NIPPON SUISAN KAISHA, LTD. (JP) 1999-09-21 US disclosed