Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441413 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2POLBAKR1C3SGMS1 | |
| SCHEMBL8438739 | 0.88 | ALDH1A1 (0.56) | ALDH1A1POLBAKR1C3MEN1RAB9A | |
| SCHEMBL8438979 | 0.88 | TAAR1 (0.58) | ALDH1A1POLBSGMS1PKMMEN1 | |
| SCHEMBL8442601 | 0.86 | TAAR1 (0.52) | ALDH1A1AKR1C3MEN1KMT2AMCL1 | |
| SCHEMBL8437940 | 0.85 | TBXAS1 (0.50) | ALDH1A1POLBSGMS1MEN1TDP2 | |
| SCHEMBL8439475 | 0.85 | TBXA2R (0.59) | AKR1C3MEN1KMT2A | |
| SCHEMBL8441089 | 0.83 | CA1 (0.53) | ALDH1A1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL8441823 | 0.79 | MCL1 (0.39) | ALDH1A1POLBKMT2AMCL1MAPT | |
| SCHEMBL11113173 | 0.77 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2POLBAKR1C3SGMS1 | |
| SCHEMBL8441801 | 0.76 | ALDH1A1 (0.55) | ALDH1A1POLBAKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |