Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438979 | 0.91 | TAAR1 (0.58) | ALDH1A1MEN1KMT2ATBXAS1MAPT | |
| SCHEMBL8442601 | 0.89 | TAAR1 (0.52) | ALDH1A1MEN1KMT2ATBXAS1AKR1C3 | |
| SCHEMBL8439475 | 0.88 | TBXA2R (0.59) | MEN1KMT2ATBXAS1AKR1C3 | |
| SCHEMBL8437940 | 0.88 | TBXAS1 (0.50) | ALDH1A1MEN1KMT2ATBXAS1MAPT | |
| SCHEMBL8441801 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATBXAS1AKR1C3 | |
| SCHEMBL8441016 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL8441089 | 0.85 | CA1 (0.53) | ALDH1A1MEN1KMT2ATBXAS1MAPT | |
| SCHEMBL8441823 | 0.81 | MCL1 (0.39) | ALDH1A1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL8441806 | 0.78 | TAAR1 (0.54) | ALDH1A1MEN1KMT2ATBXAS1MAPT | |
| SCHEMBL8441966 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TBXAS1AKR1C3MAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |