Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8438721 | 1.00 | EPHX1 (0.46) | EPHX1KCNJ1ALDH1A1GAAITGB3 | |
| Hydrochloric Acid SCHEMBL8110531 | 0.92 | EPHX1 (0.51) | EPHX1ALDH1A1GAATSHR | |
| Hydrochloric Acid SCHEMBL8108681 | 0.92 | EPHX1 (0.51) | EPHX1ALDH1A1GAATSHR | |
| Trifluoroacetic Acid SCHEMBL952786 | 0.86 | ALDH1A1 (0.55) | EPHX1ALDH1A1GAAITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7457717 | 0.86 | CTSL (0.38) | EPHX1ALDH1A1ITGB3ITGA2BITGAV | |
| Trifluoroacetic Acid SCHEMBL7456330 | 0.85 | MEN1 (0.41) | EPHX1KCNJ1ALDH1A1CTSLTGM2 | |
| Trifluoroacetic Acid SCHEMBL8104475 | 0.84 | KCNJ1 (0.40) | KCNJ1TSHR | |
| Trifluoroacetic Acid SCHEMBL7457933 | 0.84 | ALDH1A1 (0.38) | EPHX1ALDH1A1GAACTSLTGM2 | |
| Trifluoroacetic Acid SCHEMBL7457930 | 0.84 | ALDH1A1 (0.38) | EPHX1ALDH1A1GAACTSLTGM2 | |
| Trifluoroacetic Acid SCHEMBL7463523 | 0.83 | CTRB1 (0.46) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |