Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8104475

O=C(N[C@H]1CCNC1)[C@@H]1CCN1C(=O)OCc1ccc([N+](=O)[O-])cc1.O=C(O)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 1/20 0.40
CTRB1 P17538 1/20 0.40
CTSK P43235 2/20 0.38
CCR5 P51681 2/20 0.38
CTSB P07858 1/20 0.38
CTSS P25774 1/20 0.38
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
RAB9A P51151 1/20 0.37
KLK7 P49862 1/20 0.37
SIGMAR1 Q99720 2/20 0.36
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7463523 0.95 CTRB1 (0.46) CTRB1CTSKCTSBCTSSTSHR
Trifluoroacetic Acid SCHEMBL8102750 0.94 CTSK (0.45) KCNJ1CTRB1CTSKCTSBCTSS
Trifluoroacetic Acid SCHEMBL8108759 0.89 TSHR (0.47) CTRB1CTSKCTSBCTSSTSHR
SCHEMBL27461186 0.88 CTSK (0.47) CTRB1CTSKCTSBCTSSTSHR
Trifluoroacetic Acid SCHEMBL8108795 0.87 MCL1 (0.35) KCNJ1CTRB1CTSKCCR5CTSB
Trifluoroacetic Acid SCHEMBL8438721 0.84 EPHX1 (0.46) KCNJ1TSHR
Trifluoroacetic Acid SCHEMBL8439864 0.84 EPHX1 (0.46) KCNJ1TSHR
SCHEMBL8104481 0.80 CCR2 (0.38) KCNJ1CTSKCCR5CTSBCTSS
Hydrochloric Acid SCHEMBL8108681 0.76 EPHX1 (0.51) TSHRRAB9A
Hydrochloric Acid SCHEMBL8110531 0.76 EPHX1 (0.51) TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6090802-A BACTERICIDE SANKYO COMPANY, LIMITED (JP) 2000-07-18 US disclosed
EP-0882728-A1 1-METHYLCARBAPENEM DERIVATIVES SANKYO COMPANY LIMITED (JP) 1998-12-09 EP disclosed