Urea

Urea

SCHEMBL8440002

NC(N)=O.ON1CCNC1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
CHKA P35790 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
CHRNB3 Q05901 1/20 0.32
CHRNA6 Q15825 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
OR51E2 Q9H255 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1059903 0.87
Hydrochloric Acid SCHEMBL27810558 0.84
Acetic Acid SCHEMBL27866028 0.83 KMT2A (0.35) CA2CA12CA1CA9CHKA
Urea SCHEMBL28001096 0.77 CA2 (0.36) CA2CA12CA1CA9CHKA
SCHEMBL646640 0.70
SCHEMBL1058395 0.70
SCHEMBL27511083 0.70 GNAO1 (0.44) LMNA
Urea SCHEMBL6942842 0.69 GNAI3 (0.34) CA2CA12CA1CA9
Water SCHEMBL27314666 0.68
SCHEMBL142617 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748210-B1 METHODS OF USING CYCLIC POLYANIONIC POLYOL DERIVATIVES FOR REGULATING SKIN WRINKLES PROCTER & GAMBLE (US) 1999-07-14 EP disclosed
WO-1999007339-A1 COMPOSITIONS FOR VISUALLY IMPROVING SKIN THE PROCTER & GAMBLE COMPANY (US) 1999-02-18 WO disclosed
EP-0748210-A1 METHODS OF USING CYCLIC POLYANIONIC POLYOL DERIVATIVES FOR REGULATING SKIN WRINKLES THE PROCTER & GAMBLE COMPANY (US) 1996-12-18 EP disclosed
EP-0505108-B1 Compositions for regulating skin wrinkles comprising an Arg-Ser-Arg-Lys based peptide PROCTER & GAMBLE (US) 1995-10-18 EP disclosed
WO-1995023588-A1 METHODS OF USING CYCLIC POLYANIONIC POLYOL DERIVATIVES FOR REGULATING SKIN WRINKLES THE PROCTER & GAMBLE COMPANY (US) 1995-09-08 WO disclosed
EP-0505108-A1 Compositions for regulating skin wrinkles comprising an Arg-Ser-Arg-Lys based peptide THE PROCTER & GAMBLE COMPANY (US) 1992-09-23 EP disclosed