Sugi Predict

Sugi Predict / Compounds / SCHEMBL844007

SCHEMBL844007

SCHEMBL844007

COc1cccc(Cl)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.48
▸ CA12 O43570 2/20 0.48
▸ CA1 P00915 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ CA7 P43166 2/20 0.48
▸ CA9 Q16790 2/20 0.48
▸ CA14 Q9ULX7 2/20 0.48
▸ CA4 P22748 1/20 0.48
▸ KDM4E B2RXH2 2/20 0.45
▸ GAA P10253 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ L3MBTL1 Q9Y468 5/20 0.44
▸ HSP90AA1 P07900 2/20 0.44
▸ HPGD P15428 4/20 0.43
▸ MAPT P10636 3/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ CYP3A4 P08684 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27986004 0.98 ALDH1A1 (0.46) ALDH1A1CA12CA1CA2CA7
SCHEMBL146841 0.82 CA1 (0.61) ALDH1A1CA12CA1CA2CA7
SCHEMBL13970688 0.81 EPAS1 (0.49) ALDH1A1MRGPRX4
SCHEMBL12139476 0.78 ALDH1A1 (0.44) ALDH1A1CA12CA1CA2CA7
SCHEMBL30772335 0.78 CA12 (0.50) ALDH1A1CA12CA1CA2CA7
SCHEMBL78713 0.78 CA12 (0.50) ALDH1A1CA12CA1CA2CA7
SCHEMBL27509287 0.77 ALDH1A1 (0.45) ALDH1A1KDM4EGAAHTTMAPT
SCHEMBL2723162 0.77 ALDH1A1 (0.45) ALDH1A1KDM4EGAAHTTMAPT
SCHEMBL29635862 0.77 — —
SCHEMBL12541 0.77 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375614-A Synthesis method of cyclosulfamide intermediate 江西扬帆新材料有限公司 2023-07-04 — — CN claimed
CN-113248351-B Preparation method of 6-chloro-2-methoxytoluene and synthetic process of methoxyfenozide 绍兴上虞新银邦生化有限公司 2022-10-11 — — CN claimed
CN-113248351-A Preparation method of 6-chloro-2-methoxytoluene and synthetic process of methoxyfenozide 绍兴上虞新银邦生化有限公司 2021-08-13 — — CN claimed
CN-111018693-A 2-methyl-3-methoxybenzoic acid and preparation method thereof 西安正阳嘉禾化工科技有限公司 2020-04-17 — — CN claimed
CN-107793308-A A kind of synthetic method of the methoxy benzoic acid of 2 methyl 3 江苏万隆科技有限公司 2018-03-13 — — CN claimed
CN-107778167-A The preparation method of the methoxy benzoic acid of 2 methyl 3 江苏万隆科技有限公司 2018-03-09 — — CN claimed
US-12441703-B2 Carboxamides as modulators of sodium channels VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-10-14 — — US disclosed
US-12060347-B2 Bicyclic heteroaryl substituted compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2024-08-13 — — US disclosed
CN-112409226-B Substituted benzoyl compounds and application thereof 东莞市东阳光农药研发有限公司 2024-04-05 — — CN disclosed
CN-112409263-B Substituted benzoyl compounds and application thereof 东莞市东阳光农药研发有限公司 2024-04-05 — — CN disclosed
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-11-02 — — US disclosed
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-11-02 — — US disclosed
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-11-02 — — US disclosed
US-4081554-A DIURETICS, SALURETICS, URICOSURICS MERCK & CO., INC. (US) 1978-03-28 — — US disclosed
US-4012524-A DIURETICS, SALURETICS, HYPOURICEMICS, HYPOTENSIVES, ANTIEDEMICS MERCK & CO., INC. (US) 1977-03-15 — — US disclosed
US-4003927-A DIURETICS MERCK & CO., INC. (US) 1977-01-18 — — US disclosed
US-3984552-A 6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids MERCK & CO., INC. (US) 1976-10-05 — — US disclosed
US-3984465-A DIURETIC, SALURETIC AND URICOSURIC MERCK & CO., INC. (US) 1976-10-05 — — US disclosed
US-3976681-A DIURETIC, SALURETIC, URICOSURIC MERCK & CO., INC. (US) 1976-08-24 — — US disclosed
US-3966966-A DIURETICS MERCK & CO., INC. (US) 1976-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF PHGDH, G6PD, PGD ALDH1A1 222/4885CA12 1863/4885CA1 1552/4885
US-12060347-B2 Bicyclic heteroaryl substituted compounds F2, F2RL3, F12 ALDH1A1 1598/4885CA12 3794/4885CA1 3155/4885
US-12441703-B2 Carboxamides as modulators of sodium channels TRPV1, SCN2A, SCN10A ALDH1A1 2665/4885CA12 1279/4885CA1 646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.