Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 2/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 2/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920744 | 0.73 | ALDH1A1 (0.48) | MMP1MMP2MMP9CYSLTR2CYSLTR1 | |
| SCHEMBL8437945 | 0.70 | TBXAS1 (0.39) | — | |
| SCHEMBL7923998 | 0.68 | ALDH1A1 (0.45) | MMP1MMP2MMP9CYSLTR2CYSLTR1 | |
| SCHEMBL8439860 | 0.63 | MCL1 (0.44) | — | |
| SCHEMBL24576357 | 0.61 | RELA (0.43) | — | |
| SCHEMBL9186145 | 0.60 | TP53 (0.38) | — | |
| SCHEMBL27934356 | 0.60 | HDAC8 (0.44) | MMP1 | |
| SCHEMBL21117431 | 0.59 | ALDH1A1 (0.40) | — | |
| SCHEMBL9186141 | 0.59 | TP53 (0.41) | — | |
| SCHEMBL11603393 | 0.59 | FFAR4 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |