Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYBB | P04839 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442774 | 0.95 | HTR1D (0.44) | HTR1DHTR1BHTR6KDM4EMEN1 | |
| SCHEMBL8443000 | 0.93 | HTR1D (0.37) | HTR1DHTR1BNPSR1HTR6TP53 | |
| SCHEMBL8440547 | 0.84 | NPSR1 (0.38) | HTR1DHTR1BNPSR1HTR6KCNH2 | |
| SCHEMBL8440211 | 0.82 | HTR6 (0.39) | HTR1DHTR1BNPSR1HTR6TP53 | |
| SCHEMBL8668983 | 0.81 | MEN1 (0.36) | KDM4EMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8439253 | 0.80 | MAPT (0.41) | NPSR1KCNH2TP53KDM4EMEN1 | |
| SCHEMBL8440207 | 0.80 | NPSR1 (0.36) | HTR1DHTR1BNPSR1HTR6KCNH2 | |
| SCHEMBL8633727 | 0.79 | MAPT (0.41) | NPSR1KCNH2TP53KDM4EMEN1 | |
| SCHEMBL7923747 | 0.79 | KDM4E (0.41) | KCNH2KDM4EMEN1KMT2AHRH1 | |
| SCHEMBL8553022 | 0.78 | KDM4E (0.40) | KCNH2TP53KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |