Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYBB | P04839 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442772 | 0.95 | HTR1D (0.41) | HTR1DHTR1BHTR6KDM4EKMT2A | |
| SCHEMBL8442999 | 0.93 | HTR1D (0.35) | NPSR1HTR1DHTR1BHTR6KDM4E | |
| SCHEMBL8440546 | 0.84 | NPSR1 (0.38) | NPSR1HTR1DHTR1BHTR6KCNH2 | |
| SCHEMBL8670315 | 0.83 | MAPT (0.33) | KMT2AMAPTMAPK1MEN1NPC1 | |
| SCHEMBL8440210 | 0.82 | LMNA (0.39) | NPSR1HTR1DHTR1BHTR6KCNH2 | |
| SCHEMBL8668979 | 0.81 | MEN1 (0.36) | KMT2AMAPTMAPK1MEN1TSHR | |
| SCHEMBL8438828 | 0.80 | KMT2A (0.41) | NPSR1KCNH2KDM4EKMT2AMAPT | |
| SCHEMBL8440209 | 0.80 | HTR1D (0.39) | NPSR1HTR1DHTR1BHTR6KCNH2 | |
| SCHEMBL8443544 | 0.77 | HTR1D (0.36) | NPSR1HTR1DHTR1BHTR6KDM4E | |
| SCHEMBL8439249 | 0.77 | KDM4E (0.38) | NPSR1HTR1DHTR1BHTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |