Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443349 | 0.95 | CYP1A2 (0.44) | LMNATSHRHTR6CYP1A2CYP2C19 | |
| SCHEMBL8440546 | 0.84 | NPSR1 (0.38) | HTR6NPSR1HTR1DHTR1BKDM4E | |
| SCHEMBL8440207 | 0.82 | NPSR1 (0.36) | TSHRHTR6NPSR1HTR1DHTR1B | |
| SCHEMBL8440211 | 0.80 | HTR6 (0.39) | TSHRHTR6NPSR1HTR1DHTR1B | |
| SCHEMBL8443544 | 0.77 | HTR1D (0.36) | LMNATSHRHTR6NPSR1HTR1D | |
| SCHEMBL8439249 | 0.77 | KDM4E (0.38) | LMNATSHRHTR6CYP1A2CYP2C19 | |
| SCHEMBL8442772 | 0.77 | HTR1D (0.41) | LMNATSHRHTR6HTR1DHTR1B | |
| SCHEMBL8442999 | 0.76 | HTR1D (0.35) | LMNATSHRHTR6NPSR1HTR1D | |
| SCHEMBL8440547 | 0.74 | NPSR1 (0.38) | LMNATSHRHTR6NPSR1HTR1D | |
| SCHEMBL8443350 | 0.74 | HTR6 (0.44) | LMNATSHRHTR6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |