Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439249 | 0.93 | KDM4E (0.38) | NPSR1HTR1DHTR1BPTGS2HTR6 | |
| SCHEMBL8443544 | 0.93 | HTR1D (0.36) | NPSR1HTR1DHTR1BPTGS2HTR6 | |
| SCHEMBL8440207 | 0.84 | NPSR1 (0.36) | NPSR1HTR1DHTR1BHTR6KCNH2 | |
| SCHEMBL8440210 | 0.84 | LMNA (0.39) | NPSR1HTR1DHTR1BHTR6KCNH2 | |
| SCHEMBL8441755 | 0.84 | MEN1 (0.39) | NPSR1PTGS2ARPDPK1MAPT | |
| SCHEMBL8672721 | 0.80 | PTGS2 (0.40) | PTGS2PDPK1MAPTMEN1KMT2A | |
| SCHEMBL8440547 | 0.79 | NPSR1 (0.38) | NPSR1HTR1DHTR1BHTR6KCNH2 | |
| SCHEMBL8551375 | 0.79 | KDM4E (0.39) | PTGS2ARPDPK1KDM4EMAPT | |
| SCHEMBL8443349 | 0.78 | CYP1A2 (0.44) | HTR1DHTR1BHTR6KDM4EMEN1 | |
| SCHEMBL8442772 | 0.78 | HTR1D (0.41) | HTR1DHTR1BHTR6KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |