Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYBB | P04839 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440546 | 0.93 | NPSR1 (0.38) | HTR1DHTR1BHTR6PTGS2PTGDR2 | |
| SCHEMBL8439249 | 0.91 | KDM4E (0.38) | HTR1DHTR1BGALR3NR2F2LMNA | |
| SCHEMBL8442999 | 0.84 | HTR1D (0.35) | HTR1DHTR1BGALR3NR2F2LMNA | |
| SCHEMBL8441755 | 0.82 | MEN1 (0.39) | LMNAPTGS2MEN1KMT2ANPSR1 | |
| SCHEMBL8443545 | 0.80 | GALR3 (0.38) | HTR1DHTR1BGALR3NR2F2LMNA | |
| SCHEMBL8551375 | 0.79 | KDM4E (0.39) | LMNAGAASMN1; SMN2PTGS2TSHR | |
| SCHEMBL8672721 | 0.79 | PTGS2 (0.40) | LMNASMN1; SMN2PTGS2TSHRMEN1 | |
| SCHEMBL8380817 | 0.78 | MEN1 (0.34) | LMNASMN1; SMN2PTGS2TSHRMEN1 | |
| SCHEMBL8440207 | 0.77 | NPSR1 (0.36) | HTR1DHTR1BHTR6TSHRMEN1 | |
| SCHEMBL8440210 | 0.77 | LMNA (0.39) | HTR1DHTR1BLMNAHTR6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |